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Mogensen TH, Melchjorsen J, Hollsberg P, Paludan SR (2003) Activation of NF-kappaB in Virus-Infected Macrophages Is Dependent on Mitochondrial Oxidative Stress and Intracellular Calcium: Downstream Involvement of the Kinases TGF-beta-Activated Kinase 1, Mitogen-Activated Kinase/Extracellular Signal-Regulated Kinase Kinase 1, and IkappaB Kinase
Combination Treatments : Pairing glutamine inhibitors with chemotherapy, immunotherapy, or IDH2 inhibitors boosts effectiveness
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Interference with Chemotherapy : Some studies suggest that glutathione may protect cancer cells from the effects of chemotherapy , potentially reducing the treatment's efficacy